Knoxville challenger · ATP
Knoxville challenger 2022
ChallengerHard indoorKnoxville, United States6 November – 13 November 2022Prize money: 53,120 USD49 matchesAltitude: 276 mCourt: Medium-fast
Champion Ben Shelton · Final: 6-3 7-5
Final rounds
| Final | Ben Shelton vs Christopher Eubanks | 6-3 1-6 7-6(4) |
| Semifinal | Christopher Eubanks vs Michael Mmoh | 6-7(2) 7-5 6-2 |
| Semifinal | Ben Shelton vs Enzo Couacaud | 6-7(3) 6-4 6-4 |
| Quarterfinal | Christopher Eubanks vs Lucas Gerch | 6-3 6-2 |
| Quarterfinal | Michael Mmoh vs Tennys Sandgren | 6-3 6-4 |
| Quarterfinal | Ben Shelton vs Aleksandar Kovacevic | 7-5 6-4 |
| Quarterfinal | Enzo Couacaud vs Stefan Kozlov | 6-3 7-5 |
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