Guadalajara 125 Open · WTA
Guadalajara 125 Open 2022
WTA 250HardGuadalajara, Mexico19 February – 28 February 2022Prize money: 239,477 USD49 matchesAltitude: 1,554 mCourt: Slow
Champion Sloane A. Stephens · Final: 6-2 6-3
Final rounds
| Final | Sloane A. Stephens vs Marie Bouzkova | 7-5 1-6 6-2 |
| Semifinal | Marie Bouzkova vs Qiang Wang | 6-3 6-3 |
| Semifinal | Sloane A. Stephens vs Anna Kalinskaya | 3-6 7-5 0-0 ret. |
| Quarterfinal | Marie Bouzkova vs Sara Sorribes Tormo | 6-4 6-1 |
| Quarterfinal | Sloane A. Stephens vs Daria Saville | 4-6 6-3 6-2 |
| Quarterfinal | Anna Kalinskaya vs Camila Osorio | 6-4 6-1 |
| Quarterfinal | Qiang Wang vs Karolina Anna Schmiedlova | 6-2 6-3 |
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