Santa Cruz challenger · ATP
Santa Cruz challenger 2022
ChallengerClaySanta Cruz de la Sierra, Bolivia23 January – 29 January 2022Prize money: 53,120 USD43 matchesAltitude: 419 mCourt: Medium-fast
Champion Francisco Cerundolo · Final: 7-5 6-3
Final rounds
| Final | Francisco Cerundolo vs Camilo Ugo Carabelli | 6-4 6-3 |
| Semifinal | Camilo Ugo Carabelli vs Pedro Cachin | 6-3 6-2 |
| Semifinal | Francisco Cerundolo vs Hugo Dellien | 1-6 6-4 6-3 |
| Quarterfinal | Hugo Dellien vs Nicolas Alvarez | 6-1 6-4 |
| Quarterfinal | Pedro Cachin vs Fernando Verdasco | 6-3 6-1 |
| Quarterfinal | Francisco Cerundolo vs Nicolas Moreno De Alboran | 6-3 6-4 |
| Quarterfinal | Camilo Ugo Carabelli vs Murkel Dellien | 7-5 6-3 |
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