San Diego Open · ATP
San Diego Open 2022
ATP 250HardSan Diego, United States17 September – 26 September 2022Prize money: 612,000 USD39 matchesAltitude: 12 mCourt: Medium
Champion Brandon Nakashima · Final: 7-6(5) 6-3
Final rounds
| Final | Brandon Nakashima vs Marcos Giron | 6-4 6-4 |
| Semifinal | Brandon Nakashima vs Christopher O'Connell | 6-4 7-6(3) |
| Semifinal | Marcos Giron vs Daniel Evans | 6-3 7-5 |
| Quarterfinal | Brandon Nakashima vs Daniel Elahi Galan | 6-3 4-6 6-4 |
| Quarterfinal | Christopher O'Connell vs Jenson Brooksby | 6-4 4-6 7-5 |
| Quarterfinal | Daniel Evans vs Constant Lestienne | 6-1 6-3 |
| Quarterfinal | Marcos Giron vs James Duckworth | 7-6(5) 6-3 |
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