Italian Open · ATP
Italian Open 2021
Masters 1000ClayRome, Italy8 May – 16 May 2021Prize money: 2,563,710 EUR76 matchesAltitude: 54 mCourt: Medium
Champion Rafael Nadal · Final: 7-5 7-6(2)
Final rounds
| Final | Rafael Nadal vs Novak Djokovic | 7-5 1-6 6-3 |
| Semifinal | Novak Djokovic vs Lorenzo Sonego | 6-3 6-7(5) 6-2 |
| Semifinal | Rafael Nadal vs Reilly Opelka | 6-4 6-4 |
| Quarterfinal | Lorenzo Sonego vs Andrey Rublev | 3-6 6-4 6-3 |
| Quarterfinal | Novak Djokovic vs Stefanos Tsitsipas | 4-6 7-5 7-5 |
| Quarterfinal | Rafael Nadal vs Alexander Zverev | 6-3 6-4 |
| Quarterfinal | Reilly Opelka vs Federico Delbonis | 7-5 7-6(2) |
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